Pirates vs. Cubs Prediction, Odds, Picks - May 1

Data Skrive

The Chicago Cubs and Carson Kelly hit the field at PNC Park against Andrew McCutchen and the Pittsburgh Pirates on Thursday. The favored Pirates have -159 moneyline odds against the underdog Cubs, who are listed at +134. Pittsburgh is favored on the run line (-1.5 with +139 odds). A 7.5-run total has been set for the matchup.

Here’s everything you need from a betting perspective on the Pirates-Cubs game, regarding the run line, moneyline and total, plus expert picks.

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Check out the best moments between the Chicago Cubs and the Pittsburgh Pirates.

Pirates vs. Cubs Game Information & Odds

When: Thursday, May 1, 2025 at 12:35 p.m. ET
Where: PNC Park in Pittsburgh, Pennsylvania
How to watch on TV: SportsNet PT and MARQ

Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Pirates -159 +134 7.5 -110 -109 -1.5 +139 -165

Pirates vs. Cubs Prediction

Score Prediction: Cubs 4, Pirates 3
Total Prediction: Over 7.5 runs
Win Probabilities: Pirates 57%, Cubs 43%

Pirates vs. Cubs Betting Insights

The Pirates have been favorites in 11 games this season and won five (45.5%) of those contests.
Pittsburgh has played as favorites of -159 or more twice this season and split those games.
The moneyline for this contest implies a 61.4% chance of a victory for the Pirates.
The Cubs have won in seven, or 46.7%, of the 15 contests they have been named as odds-on underdogs this year.
Chicago has a win-loss record of 2-1 when favored by +134 or worse by bookmakers this year.
The moneyline set for this matchup implies the Cubs have a 42.7% chance of walking away with the win.

Pirates Recent Betting Performance

In the last 10 games, the Pirates have been named the moneyline favorite by oddsmakers only twice, and they lost both games.
Over their last 10 outings (all had set totals), the Pirates combined with their opponents to go over the run total six times.
The Pirates have put together a 5-5-0 record against the spread over their past 10 games.

Pirates Recent Stats

Stat Avg/Total Record 3-7 Runs Per Game 3.5 HR 10 ERA 4.81 K/9 7.3

Pirates Player Insights

Oneil Cruz has racked up a team-best eight home runs and 16 runs batted in.
Cruz is 10th in home runs and 48th in RBI among all hitters in baseball.
McCutchen is batting .275 with five doubles, three home runs and 11 walks.
McCutchen carries a two-game streak with at least one hit into this matchup. During his last five outings he is hitting .350 with two doubles, a home run, a walk and an RBI.
Isiah Kiner-Falefa has accumulated a team-high batting average of .289.
Kiner-Falefa is on a four-game hitting streak entering this contest. In his last five games he is hitting .278 with a walk.
Enmanuel Valdez has three doubles, two triples, two home runs and 10 walks while hitting .219.

Cubs Recent Betting Performance

In four games as underdogs over the last 10 matchups, the Cubs have a record of 2-2.
In their last 10 games with a total, the Cubs and their opponents have failed to hit the over four times.
Over their last 10 games, the Cubs are 5-5-0 against the spread.

Cubs Recent Stats

Stat Avg/Total Record 6-4 Runs Per Game 5.9 HR 16 ERA 4.06 K/9 7.9

Cubs Player Insights

Kyle Tucker leads the Cubs in home runs (seven) and runs batted in (26).
Tucker ranks 19th in homers and fifth in RBI among all batters in MLB.
Pete Crow-Armstrong is batting .284 with 10 doubles, a triple, six home runs and six walks.
Crow-Armstrong ranks 30th in homers and 17th in RBI among all major league hitters this year.
Seiya Suzuki leads the Cubs with seven long balls while collecting a team-leading batting average of .298.
Kelly leads the Cubs with seven long balls.

Check out the best moments between the Chicago Cubs and the Pittsburgh Pirates.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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