The Arizona Diamondbacks (12-9) and the Chicago Cubs (14-9) wrap up a 3-game series Sunday. First pitch from Wrigley Field is at 2:20 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Diamondbacks vs. Cubs odds and make our expert MLB picks and predictions for the best bets.
Season series: Cubs lead 4-2
The Diamondbacks dropped their second straight game Saturday following a 5-game winning streak and victories in 7 of their previous 8. After a wild 13-11 loss in Friday’s series opener, Arizona SP Zac Gallen surrendered 6 runs over 6 innings in a 6-2 defeat. RF Corbin Carroll had 3 hits, including his seventh home run of the season, while 2B Tim Wawa added his second homer of the year.
Cubs DH Seiya Suzuki hit his sixth homer and 1B Michael Busch had 2 hits, homering for the fifth time this season and driving in 2 in Saturday’s win. Chicago has won 5 of its last 7 games.
Diamondbacks at Cubs projected starters
RHP Merrill Kelly vs. RHP Jameson Taillon
Kelly (3-1, 5.57 ERA) makes his fifth start. He has a 1.33 WHIP, 4.3 BB/9 and 6.9 K/9 through 21 innings.
- Last start: Win, 6 IP, 1 ER, 3 H, 1 BB, 9 K in 10-4 victory at Miami Marlins Tuesday
- 2025 road stats: 1-1, 9.31 ERA (10 ER, 9 2/3 IP), 12 H, 4 BB, 11 K in 2 starts
- Is 3-1 with 3.49 ERA in 7 career starts vs. Cubs
Taillon (1-1, 5.40 ERA) makes his fifth start. He has a 1.25 WHIP, 2.1 BB/9 and 7.5 K/9 through 21 2/3 innings.
- Last start: No-decision, 5 1/3 IP, 2 ER, 4 H, 1 BB, 4 K in 10-4 defeat at San Diego Padres Monday
- 2025 vs. Diamondbacks: 1 road start (March 28), loss, 4 1/3 IP, 6 ER, 9 H, 0 BB, 1 K in 8-1 defeat
- Has 2.59 ERA in 3 starts since facing Arizona
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Diamondbacks at Cubs odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:50 a.m. ET.
- Moneyline (ML): Diamondbacks +110 (bet $100 to win $110) | Cubs -130 (bet $130 to win $100)
- Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-210) | Cubs -1.5 (+180)
- Over/Under (O/U):7 (O: -120 | U: +100)
Diamondbacks at Cubs picks and predictions
Prediction
Diamondbacks 6, Cubs 4
Moneyline
The Diamondbacks have not been swept in a series this season. The Cubs have only completed 1 sweep so far, taking all 3 games at the Athletics March 31 to April 2.
Two of Kelly’s wins have come after an Arizona loss.
The Cubs have not swept the Diamondbacks in a 3-game home series since 2015.
BET DIAMONDBACKS (+130).
Run line/Against the spread
All 10 of the Diamondbacks’ covers this season have been outright wins. And with -210 odds for them to cover +1.5, it makes much more sense to bet the plus odds on the moneyline.
PASS.
Over/Under
All 4 of Kelly’s starts have had totals of 7 or higher. All 6 meetings have had totals of at least 7.
Arizona has had 10 straight games with totals of at least 7 runs.
BET OVER 7 (-120).
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